Antimicrobial activity of Bis-salicylaldehyde Ethylenediamine Schiff Base and Its Lanthanoids (III) Complexes

Schiff base readily form complex with metal ions and the resultant complexes especially from transition metals were extensively used in many fields of human endeavor including antimicrobial therapy. However, potentials Lanthanide-Schiff as an agent have not been adequately studied. This study aims to synthesize determine activity Bis-salicylaldehyde ethylenediamine Base its Lanthanoids (III) Complexes. The Dysprosium (III), Gadolinium Neodymium Samarium derived Salicylaldehyde synthesized under reflux condition ethanol their determined using disc diffusion method. was a shiny crystalline yellow yield 93% various sheds ranges pale dark, percentage between 94-98%. had good against C. albican (32mm at 100mg/ml), A. niger (20mm 100mg/ml) Fusarium Spp (17mm but low (07-11mm or no (06mm all fungal isolates. antibacterial E. coli (8mm Pseudomonas (6mm Klebsiella (13mm lower than that Ampiclox (between 17 20mm) even though, Lanthanoid 8 14mm higher Bis-salicylaldehydeethylenediamine still Ampiclox. Considering in-vitro exhibited by bacterial isolates, both will be potential could pontential antifungal agent. We therefore, recommend further researches geared toward exploring full for